Not known Details About akorn codeine
Not known Details About akorn codeine
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, ritonavir) or discontinuation of the cytochrome P450 3A4 inducer such as rifampin, carbamazepine, and phenytoin, could end in an increase in codeine plasma concentrations with subsequently greater metabolism by cytochrome P450 2D6, causing greater morphine levels, which could improve or extend adverse reactions and could bring about perhaps lethal respiratory despair.
Promoting or giving away Promethazine Hydrochloride and Codeine Phosphate Oral Remedy might harm Some others, which is towards the legislation. Inform your healthcare provider For those who have ever abused or been dependent on Liquor, prescription medicines or street drugs.
g., All those with proof of enhanced intracranial pressure or brain tumors), promethazine HCl and codeine phosphate oral Resolution might lower respiratory drive, plus the resultant CO2 retention can additional raise intracranial pressure. Also, opioids make adverse reactions which will obscure the clinical study course of individuals with head injuries.
Place the combination inside of a container such as a sealed plastic bag and throw it absent in the household trash. It's also possible to comply with your point out or nearby tips regarding how to securely throw away Promethazine Hydrochloride and Codeine Phosphate Oral Remedy.
Due to likely for promethazine to reverse epinephrine’s vasopressor effect, epinephrine shouldn't be utilized to deal with hypotension related to promethazine overdose.
When your pharmacist is not able to uncover an analogous generic medication for the a person you are working with from A further maker, Tsourounis endorses finding in contact with all your healthcare company to discuss if you will discover some other possibilities obtainable.
Be certain precision when prescribing, dispensing, and administering promethazine HCl and codeine phosphate oral Remedy. Dosing problems can result in accidental overdose and Demise.
Endocrine/Metabolic: Cases of serotonin syndrome, a likely lifetime-threatening problem, have already been claimed in the course of concomitant usage of opioids with serotonergic medications.
Use warning When it comes to the use of promethazine HCl and codeine phosphate oral website Remedy in individuals sixty five a long time of age or more mature.
Wocklean is often a Drug Free syrup that has been specifically formulated to aid the thoughts and system reach a whole new condition of peace. Relax & unwind following a prolonged day and drift peacefully right into a point out of tranquility.
Codeine wasn't mutagenic during the in vitro bacterial reverse mutation assay or clastogenic within the in vitro Chinese hamster ovary (CHO) mobile chromosomal aberration assay.
Stay away from the usage of promethazine HCl and codeine phosphate oral Option in people who will be having inhibitors of CYP2D6.
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Postmarketing cases of respiratory melancholy, like fatalities have already been described with use of promethazine in pediatric patients.